The main character (Hyakkimaru), who lacks as much as 48 body parts, obtains a fake body and eliminates 48 monsters that were made from his body to retrieve his missing body parts.
It also highlights the new opening theme song by ASIAN KUNG-FU GENERATION along with the ending theme song from Eve.
Plot Concept: The setting is the middle of the Muromachi Period, during the 1470s after the Wars of Onin and Bunmei.