Writer Natsu Hyūga announced on October 30 that their Kuri Hime Ayakashi Yobanashi novel series is inspiring a manga adaptation that will debut in the February 2025 issue of Ichijinsha’s Monthly Comic Zero-Sum magazine on December 27.
Nekokurage’s The Apothecary Diaries manga adaptation launched in Square Enix’s Monthly Big Gangan magazine in May 2017.
Minoji Kurata later launched a separate manga adaptation titled Kusuriya no Hitorigoto: Mao Mao no Kōkyū Nazotoki Techō in Shogakukan’s Monthly Sunday GX magazine in August 2017.
Hyūga later reuploaded the original story on Shōsetsuka ni Narō in November 2017 with agreement from the publisher.