Hiroyuki Seshita (Ajin), who previously co-directed the anime adaptation of Nihei’s Knights of Sidonia manga series, is directing the film at Polygon Pictures.
Saori Hayami will play Sanakan, a protective system known as a Safeguard that is intent on annihilating and exterminating humans.
The film itself is also inspiring an upcoming manga adaptation by artist Kōtarō Sekine (Ninja Slayer Kills) that will debut on April 26.
The official website for the new anime film of Tsutomu Nihei’s Blame! manga revealed a new cast member on Friday.