Mézières and writer Cristin began publishing the science-fiction graphic novel series Valérian et Laureline in 1967.
The graphic novel series also inspired a live-action film in 2017.
The French newspaper Le Monde reported on Sunday that artist Jean-Claude Mézières passed away on Sunday.
Mézières and Cristin published the Les Cercles du Pouvoir graphic novel in 1994, which featured a flying taxi that would later be included in the film.