The manga inspired a 12-episode television anime series in 2008, and then inspired the 13-episode Yozakura Quartet ~Hana no Uta~ television anime in 2013.
The manga also inspired the Yozakura Quartet ~Hoshi no Umi~ OVA and the Yozakura Quartet ~Tsuki ni Naku~ OVA in 2010 and 2013, respectively.
Suzuhito Yasuda revealed on Twitter on Saturday that their Yozakura Quartet manga will enter its final arc this year.
Kodansha Comics published the 27th volume on April 13, and will publish the 28th volume on January 18.