Megane no Mahou features the voices of Ayana Taketatsu as Nanami, Miyu Iriho as Hikaru, Kayoko Ohkubo as Minami, and Mizuha Kuraoka as Nozomi.
The story of Megane no Mahou follows Nanami and Hikaru, a pair of childhood friends.
Tatsunoko Production and Chugai Pharmaceutical have teamed up for an animated short film entitled Megane no Mahou (“The Magic of the Glasses”) which seeks to raise awareness about the chronic medical condition Rheumatoid arthritis.